Figure 6: Rate-Dependence of Conduction Slowing

(A) Rate-dependent conduction slowing during hypokalemia in wedges from Ctrl (n = 6) and MI/iAL (n = 5) animals. CV at each rate is normalized to CVb. (B) Corresponding average linear slope of normalized CV restitution curves in Ctrl and MI/iAL wedges during hypokalemia at a pacing cycle length (PCL) <250 ms. (C) Representative depolarization isochrone maps from Ctrl and MI/iAL wedges. Abbreviations as in Figures 1 and 4.