Figure 6: Cardiomyocyte-Targeted Nox4 Alters MMP-2 Activity Profile After I/R

Left ventricular matrix metalloproteinase (MMP)-2 activity measured by using gelatin zymography. (A) Representative zymogram. (B) Mean data. (C) mRNA levels of MMP-2 in the left ventricle of WT and TG hearts after ischemia/reperfusion (I/R). n = 5 to 6 per group. #Significant interaction according to 2-way analysis of variance. Abbreviations as in Figures 1, 2, and 5.



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