Figure 5: Percentage of LDGs to Spontaneously Form NETs Is Associated With Circulating Platelet Counts

(A) The product of platelets and LDGs in circulation is associated with NCB; however, (B) this relationship is absent with the product of platelets and NDGs. (C) LDGs spontaneously form NETs at a (D) higher frequency than NDGs (n = 9). Data are represented as mean ± SEM. Significance was established by an unpaired Mann-Whitney Student’s t-test and set at ***p < 0.001. (E) The percentage of LDGs (n = 8) to undergo spontaneous NETosis is associated with the frequency of circulating platelets. Abbreviation as in Figures 1, 2, and 3.