Figure 4: STAT3 Phosphorylation in Murine Myocardium After Infusion of Human Plasma Dialysates Obtained Before and After RIPC

Time courses of phosphorylation of (A) signal transducer and activator of transcription 3 (STAT3), (B) STAT5, (C) protein kinase B (AKT), and (D) extracellular-regulated kinase 1/2 (ERK1/2) in murine myocardium perfused with human plasma-dialysates obtained at baseline (before) as well as at different time points after RIPC and exemplary Western blots, respectively. Data are presented as median with interquartile ranges of n = 20 at each time point; *p < 0.05 versus baseline. d = day; RIPC = remote ischemic pre-conditioning; Ser = serine; Thr = threonine; Tyr = tyrosine.