Figure 4: Respiratory Control Index of Isolated Mitochondria

The respiratory control index is defined as the ratio of state 3 to 4 respiration. Control (n = 8), P188 (n = 10), delayed P188 (n = 6), and PEG (n = 6) groups were compared as indicated. Complex I substrates (A) and complex II substrates (B) were used. Error bars represent SEM. Statistical significance (p < 0.05) denoted as: *comparing infarct to nonischemic territory from the same treatment group, and #comparing infarct tissue harvested from the P188 group with infarct tissue from all other groups. Abbreviations as in Figure 1.