Figure 4: Cardiomyocyte-Specific Knock-In miR-24 Ameliorates Ischemia/Reperfusion Injury

(A) Quantitative polymerase chain reaction analysis of miR-24 expression in hearts of WT and transgenic mice [miR-24 tg] (normalized to U6). (B) Schematic protocol for myocardial I/R surgery. (C) Representative images of WT and transgenic mice myocardial tissue slices stained with Evans blue and triphenyl tetrazolium chloride. (D) Quantitation of infarct risk area. (E) Quantitation of infarct area expressed as percentage of the nonperfused risk area during coronary occlusion. Abbreviations as in Figure 1.



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