Figure 4: CM-Specific SMAD4 Deletion Induces Cardiac Remodeling

Morphometric studies were performed at the end of 4 weeks after TAM treatment. (A) HW to TL. (B) LW to TL. (C) Quantification of cardiomyocyte CSA. (D) Masson’s trichome staining. Representative trichome-stained LV regions. (E) Quantification of LV fibrosis. Scale bar = 30 μm. Abbreviations as in Figures 1, 2, and 3.



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