Figure 4: Benefit of Cardiosphere-Derived Cell Treatment Is Not Related to Decreased Cardiac Hypertrophy

Cardiac anterior wall (AW) and posterior wall (PW) thickness by echocardiography (A), heart weight and heart weight/body weight ratio (B), and cross-sectional cardiomyocyte area (CSA) (C) are equally elevated in placebo- and cardiosphere-derived cell (CDC)–treated rats relative to control. n = 10 for control rats, n = 15 for placebo-treated rats, and n = 18 for CDC-treated rats in A; n = 6, n = 11, and n = 14, respectively, in B; n = 5 in each group in C. *p < 0.05 versus placebo- and CDC-treated rats by analysis of variance.