Figure 3: Ticagrelor and NETosis Biomarkers in Pneumonia Patients

The delta change at 24 and 48 h after dosing for the MPO-NE NETosis assay (A) and circulating dsDNA (B) were measured in placebo patients (open circles) and ticagrelor patients (filled circles) that had samples through 48 h after dosing. Significant changes are indicated by an asterisk. dsDNA = doubled-stranded DNA; MPO = myeloperoxidase; NE = neutrophil elastase.



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