Figure 3: Effects of L-Phe on Aortic BH

Effects of L-phe on aortic levels of (A) BH4, (B) superoxide, (C) BH2, and (D) biopterin after short-term (100 mg·kg−1 L-phe, oral gavage, 4 h) and long-term administration (2.5% L-phe in drinking water for 60 days, n = 6) in SHR. The datasets shown represent the mean ± SEM where *p < 0.05, **p < 0.01, and ***p < 0.001. Exact p values are in the Supplemental Data. ROS = reactive oxygen species; SOD = superoxide dismutase; other abbreviations as in Figure 1.