Figure 2: Serum Caffeine and Hemodynamic Indices in Protocol 1

Serum caffeine levels and hemodynamic changes. An expected significant increase was seen in systemic caffeine levels following caffeine infusion from 1.7 ± 0.5 to 20.3 ± 1.2 (A) (p < 0.0001 by paired t test). This had no significant effect on the heart rate (B) or blood pressure (C) graph. Box and whiskers represent the median and 5th and 95th percentiles, respectively. Abbreviations as in Figure 1.



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