Figure 2: Post-Ischemic Loss of Function Is Attenuated in Rad

(A) Representative M-mode echocardiographic tracings of wild-type (WT) and Rad−/− mice 4 weeks after myocardial infarction (MI). (B,C) Ejection fraction and fractional shortening for sham and MI (circles and squares, respectively) WT (closed) and Rad−/− (open) mice. (D,E) Left ventricular interior dimension values for WT (closed) and Rad−/− (open) at diastole (LVIDd; D) and systole (LVIDs; E). (F) Left ventricular posterior wall thickness at diastole (LVPWd). (G) Left ventricular anterior wall thickness at diastole (LVAWd). N = 19 MI and 28 sham Rad−/− and 30 MI and 38 sham WT mice per group. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001 versus WT MI.