Figure 2: Nox4 Overexpression Alters Basal Inflammatory Profile in the Heart

(A and B) Staining and quantification of macrophages (F4/80+ cells, arrows) in cardiac sections from TG and WT mice. Scale bar: 100 μm. (C to G) Messenger ribonucleic acid (mRNA) expression levels of macrophage-specific markers and chemo-attractant molecules in TG and WT heart. n = 5 to 6 per group. EMR1 = EGF-like module-containing mucin-like hormone receptor-like 1; CCR2 = C-C chemokine receptor type 2; CCL2 = C-C motif chemokine ligand 2; CCL5 = C-C motif chemokine ligand 5; VCAM = vascular cell adhesion molecule; other abbreviations as in Figure 1.



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