Figure 8: Immunohistochemical Effects of ISO Versus ISO/3AB (Representative Images)

Effects of ISO on 3-NT, TXNIP, and PAR expression in the myocardium, in the presence of ISO and in the absence of the poly(ADP-ribose) polymerase-1 inhibitor 3AB (ISO/3AB). 3-NT accumulation is shown in (A) ISO-treated myocardium and (B) ISO/3AB-treated myocardium. TXNIP accumulation is shown in (C) ISO-treated myocardium and (D) ISO/3AB-treated myocardium. PAR accumulation is shown in (E) ISO-treated myocardium and (F) ISO/3AB-treated myocardium. Abbreviations as in Figures 3 and 6.