Figure 7: JP2 Overexpression Initially Preserves T-Tubule Integrity in CAPN1-OE Mice

(A and B) Representative in situ confocal images of T-tubules in LV and RV myocytes from WT, CAPN1-OE, and CAPN1-OExJP2-OE mice at 3 weeks (A) and 5 weeks (B) of age. (C, D) Average TTpower in LV and RV myocytes from WT, CAPN1-OE and CAPN1-OExJP2-OE mice at 3 weeks (C) and 5 weeks (D) of age. n = 4 to 6 hearts for each group. **p < 0.01 versus age-matched WT; †p < 0.05 versus age-matched CAPN1-OE. RV = right ventricle; other abbreviations as in Figures 4 and 5.