Figure 6: Lack of Cardiac Myocyte Fstl1 in HFpEF Does Not Affect Cardiac Fibrosis

(A) Cardiac fibrosis in the left ventricle (LV) (left, representative Masson trichrome images, original magnification ×400) and myocardial fibrosis area (right) in WT and cFslt1-KO mice subjected to aldosterone (HFpEF) or saline (Sham) infusion. (B) Collagen 1 and 3 mRNA expression in WT and cFslt1-KO mice after aldosterone (HFpEF) or saline (Sham) infusion. n = 6 to 12 mice/group. Data are mean ± SEM. Statistical analysis by analysis of variance followed by (A) Newman-Keuls multiple comparison tests and (B) Kruskal-Wallis test followed by Dunn test.