Figure 6: JP2 Expression Progressively Declines in CAPN1-OExJP2-OE Mice

(A) Calpain activity assay in heart lysates from WT, CAPN1-OE, and CAPN1-OExJP2-OE mice at different ages. (B, C) Representative Western blot (B) and summary data (C) of JP2 expression in heart lysates WT, CAPN1-OE, and CAPN1-OExJP2-OE mice. n = 6 to 11 per group. *p < 0.05, **p < 0.01 versus age-matched WT; †p < 0.05, ††p < 0.01 versus age-matched CAPN1-OE. Abbreviations as in Figure 5.