Figure 6: Impact of GLC Receptor Antagonist on Cardiac Hypertrophy

(A) Representative histological section of ventricle by hematoxylin and eosin staining of the heart from each treatment group as indicated. (B) Tissue weight measured at week 5 post-TAC from each treatment group as indicated, including HW versus BW (HW/BW), left ventricle weight versus BW (LVW/BW), and lung weight versus BW (LW/BW). *p < 0.05 versus sham. (C) Representative images of tissue section of left ventricles stained with wheat germ agglutinin from each treatment group as indicated. (D) Quantification of cardiomyocyte cross-sectional area in left ventricles of hearts from different treatment groups as indicated. *p < 0.05 versus Control, #p < 0.05 versus TAC. Abbreviations as in Figures 1, 3, and 5.