Figure 6: Histological Analysis of LV and Liver

(A) Hematoxylin and eosin and Masson's trichrome staining were performed on liver and transmural sections of LV (original magnification 20×; presented image magnification 7×) 9.0 ± 0.2 weeks after intravenous injection of saline, AAV8.UCn2 (1.9 × 1013 gc/kg) and AAV8.UCn3 (2 × 1013 gc/kg). (B) Evaluation of fibrosis was performed using ImageJ software. AAV8.UCn2 and AAV8.UCn3 delivery were not associated with histological abnormalities. Standard is the control for Masson's trichrome. Con = control; other abbreviations as in Figures 1 and 2.