Figure 6: Functional Effect of PP2Ce Expression on SR Calcium Homeostasis in Adult Rat Cardiomyocytes

(A) Representative images of calcium transients from control rat myocytes at basal and following ISO (0.1 μmol/l) treatment. (B) Representative recording of calcium signal (F/F0) at basal and post-ISO treatment in LacZ-expressing rat adult cardiomyocytes. (C) Representative recording of calcium signal at basal and post-ISO treatment in PP2Ce-expressing rat adult cardiomyocytes. (D) Summary data of changes in calcium amplitude and decay time in adult cardiomyocytes expressing LacZ (n = 5) versus PP2Ce (n = 3) between basal and post-ISO treatment. *p < 0.05; **p < 0.01 LacZ versus PP2Ce, respectively. ⊿ = the difference between post- and pre-ISO treatment; other abbreviations as in Figures 2, 3, and 4.

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