Figure 5: STAT3 Inhibition With Stattic Abolished the Protection by Dialysates of Human Plasma Obtained After RIPC in Murine Myocardium

(A) Effect of Stattic (signal transducer and activator of transcription 3 [STAT3] inhibitor) on infarct size and (B) STAT3 phosphorylation in murine myocardium perfused with dialysates of human plasma obtained before (baseline) as well as 30 min and 6 days after RIPC for n = 7 each; *p < 0.05 versus without Stattic. d = day; LV+RV = left and right ventricle; RIPC = remote ischemic pre-conditioning; Tyr = tyrosine.