Figure 5: Glucagon and Glucagon Antagonism in Pressure-Overload Induced Cardiac Hypertrophy

Illustration of treatment regiments for pressure overload–induced heart failure by GLC receptor antagonist either at the onset of the transaortic surgery (transaortic constriction [TAC] + REMD) or 2 weeks after (TAC + REMD therapy). Abbreviations as in Figure 1.