Figure 5: GMCT Reduces Electrical Remodeling During AF Progression

(A) Dominant frequency (DF) in LA (N = 8 for saline- and GMCT-treated groups) measured in vivo (#p < 0.05 vs. saline-treated group). (B) Representative dominant frequency (DF) maps during AF optical mapping in saline-treated (top) and GMCT-treated hearts (bottom). (C) maximal DF, (D) number of rotations, (E) density of singularity points (SP), and (F) SP trajectory area in optical mapping for saline-treated (N = 6) and GMCT-treated hearts (N = 6). *p < 0.05, **p < 0.01. Abbreviations as in Figure 4.