Figure 5: Calcium Retention Capacity of Isolated Mitochondria

The cumulative calcium infused up to the point of mitochondrial permeability transition pore opening is compared for control (n = 8), P188 (n = 10), delayed P188 (n = 6), and PEG (n = 6) groups as indicated. Substrates specific for complex I (A) and complex II (B) were used. Error bars represent SEM. Statistical significance (p < 0.05) denoted as: *comparing infarct to nonischemic territory from the same treatment group, and #comparing infarct tissue harvested from the P188 group with infarct tissue from all other groups. Abbreviations as in Figure 1.