Figure 5: Ca

(A) Representative Ca2+ transient traces from cardiomyocytes (CMs) bathed in Tyrode’s solution (control cells) or pre-conditioned with media collected from AE cells with or without stretch and addition of TRPC-6 pore-blocking Ab. (B) Bar graphs showing Ca2+ transient amplitude and frequency in CMs pre-conditioned with media from AE cells with or without stretch and addition of TRPC-6 pore-blocking Ab. All values are mean ± SEM. *p < 0.025 versus control cells; p < 0.001 versus nonstretched cells (without Ab). See Supplemental Videos 5, 6, and 7. iPS = induced pluripotent stem; other abbreviations as in Figures 1 and 2.