Figure 4: Inflammatory Cytokine Quantification at the Implant Surface In Vivo

(A) Immunohistological quantification of anti-inflammatory cytokines IL-10 (top) and transforming growth factor (TGF)-β (bottom). (B) Representative images of IL-10 (top) and TGF-β (bottom) expression at the implant surface stained in white and yellow respectively. (C) Immunohistological quantification of pro-inflammatory cytokines IL-1β (top) and tumor necrosis factor (TNF)-α (bottom). (D) Representative images of IL-1β (top) and TNF-α (bottom) expression at the implant surface stained in purple and orange respectively. Dotted lines represent the interface between tissue (above) and implant (below). Scale bar represents 40 μm; n = 5 per group. Abbreviations as in Figure 1.