Figure 4: Histological Assessment of Renal Denervation

(A) Representative histological image of the renal sympathetic nerve as determined by tyrosine hydroxylase (TH) staining (red arrows) to show its distribution at the proximal, mid, and distal segments of renal arteries in the control and renal denervation (RD) groups. (B) Histological examination on the renal sympathetic nerve as determined by the immunofluorescence staining of TH-positive nerve in the control and RD groups. (Top) The percent area of TH-positive nerve at the proximal, mid, and distal segments of the renal arteries in the control and RD groups. (Bottom) The representative image of the immunofluorescence staining of TH-positive nerve (red arrows) at the proximal, mid, and distal segments of the renal arteries in the control and RD groups.