Figure 4: Histological Appearance of Pericardium and Myocardium 4 Weeks After Pericardial Instrumentation and Gel Delivery Suggest Mild Inflammatory Response

(A) On gross histologic examination, pericardium had normal thin and translucent appearance 4 weeks after hydrogel deliver. After formalin fixation and staining with hematoxylin and eosin (original magnification 10x), pericardium overlying the left atrium (B) and right ventricle (C) showed normal histologic appearance. (D) In some animals a small 1-cm2 area of thickening and increased cellularity was seen at the site of pericardial puncture involving the visceral pericardium.

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