Figure 4: Diet Modulates Cardiac Function in Mice

Mice fed a Western diet and a high–saturated fatty acids (SFAs) diet presented higher body weight (B), despite similar caloric intake (A) compared with standard diet and compared with high–unsaturated fatty acids (UFAs) diet. Western diet and high-SFA diet-fed mice presented diastolic dysfunction (C, D) after 8 weeks. High-UFA-fed mice presented preserved cardiac diastolic function, which was not different compared with standard diet.