Figure 3: Models for Computing vFFR

The imaging and pressure input data for both novel models are those collected during routine coronary angiography (image data in yellow and aortic pressure data in green). The parameters of CMV physiology must be estimated (red). The type of simulation used to calculate vFFR values are shown in the blue boxes. vFFRps-trns is a function of 9 parameters, whereas vFFRsteady is a function of 4. Pseudotransient flow can be reconstructed using a 1D flow model representing the 3D vessel geometry coupled to the 0-dimensional Windkessel model. C = compliance; CMV = coronary microvasculature; R = resistance; vFFR = virtual fractional flow reserve; Z = impedance.