Figure 3: Left Ventricular Remodeling

(Upper panel) Left ventricular (LV) weight, collagen density, infarct size, and tissue perfusion in the ‘viable’ part of the LV determined 90 days after sham surgery in untreated Wistar (white bars; n = 14) and 90 days after 45-min transient ischemia in placebo-treated I/R Wistar (black bars; n = 16), early long-term (up-hatched bars; n = 14) or delayed long-term gevokizumab-treated I/R Wistar (down-hatched bars; n = 15). (Lower panel) LV weight, collagen density, infarct size, and tissue perfusion in the ‘viable’ part of the LV determined 90 days after sham surgery in untreated Goto-Kakisaki (white bars; n = 10) and 90 days after 20-min transient ischemia in placebo-treated I/R Goto-Kakisaki (black bars; n = 15), early long-term (up-hatched bars; n = 15) or delayed long-term gevokizumab-treated I/R Goto-Kakisaki (down-hatched bars; n = 15). *p < 0.05 versus untreated sham. †p < 0.05 versus untreated I/R.