Figure 3: Ceramide Metabolism in Rats

(A) Myocardial ceramide metabolism at 4 h after acute myocardial infarction (AMI). Myocardial ceramide levels in sham (n = 3) and AMI model (n = 6) at 4 h post-ligation of the left anterior descending artery. Myocardial ceramide levels in healthy control subjects (n = 3) were measured once. (B) Plasma ceramide metabolism at 4 h after AMI. Myocardial ceramide levels in sham (n = 3) and AMI model (n = 6) at 4 h post-ligation of the left anterior descending artery. Plasma ceramide levels in healthy control subjects (n = 3) were measured once. Values are mean ± SD. p values by 2-way analysis of variance and Bonferroni test. *p < 0.05; **p < 0.01; and ***p < 0.001.