Figure 2: Patients With JPH2 Mutation A405S Develop HCM With LVOTO

(A and B) Echocardiography of a patient with HCM JPH2 mutation A405S showing asymmetrical septal hypertrophy denoted by a red arrow, and (C) LVOTO evidenced by (D) color Doppler flow mapping. (E to H) Bright-blood CMR depicting left ventricular basal septal hypertrophy (red arrow) in diastole (E) and (F) systole, with corresponding transverse CMR in diastole (G) and systole (H). Scale bars = 2.0 cm. CMR = cardiac magnetic resonance imaging; other abbreviations as in Figure 1.