Figure 2: Molecular Pathology of BAG3-Mediated Autophagy During Hypoxia-Reoxygenation

The figure illustrates the multiple pathways through which B-cell lymphoma 2 (Bcl-2)–associated anthanogene (BAG3) acts to mediate autophagy and how the expression of green fluorescent protein (GFP) (green)–red fluorescent protein (RFP) (red-orange) reporter gene can be used to quantify autophagy flux.

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