Figure 2: Left Ventricular Hemodynamics

(Upper panel) Left ventricular end-systolic pressure (LVESP), left ventricular end-systolic pressure-volume relation (LVESPVR), left ventricular end-diastolic pressure (LVEDP), and left ventricular end-diastolic pressure-volume relation (LVEDPVR) determined 90 days after sham surgery in untreated Wistar (white bars; n = 14) and 90 days after 45-min transient ischemia in placebo-treated I/R Wistar (black bars; n = 16), early long-term (up-hatched bars; n = 14) or delayed long-term gevokizumab-treated I/R Wistar (down-hatched bars; n = 15). (Lower panel) LVESP, LVESPVR, LVEDP, and LVEDPVR determined 90 days after sham-surgery in untreated Goto-Kakisaki (white bars; n = 10) and 90 days after 20-min transient ischemia in placebo-treated I/R Goto-Kakisaki (black bars; n = 15), early long-term (up-hatched bars; n = 15) or delayed long-term gevokizumab-treated I/R Goto-Kakisaki (down-hatched bars; n = 15). *p < 0.05 versus untreated sham. †p < 0.05 versus untreated I/R.