Figure 2: Effect of ApoA-I Raising by Lentiviral Gene Transfer on Late-Stage Aortic Sinus Atheroma

Aortic sinus sections were quantified histologically for plaque area (A), F4-80+ macrophage content (B), extracellular lipid content (C), and α-actin+ SMC content (D). Upper panels of A, B, and D display images of representative sections (scale bar indicates 200 μm). Data are mean ± SD; n = 8 mice/treatment. LVApoA-I = lentivirus overexpressing apolipoprotein A-I; LVGFP = lentivirus overexpressing green fluorescence protein; other abbreviations as in Figure 1.

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