Figure 1: Mechanical Properties of Electrospun Silk Scaffolds for Vascular Grafting

(A) Scanning electron micrograph of electrospun silk. Scale bar = 10 μm. (B) Cross section of electrospun silk (white), demonstrating scaffold porosity (black). (C) Representative amine I Fourier transform infrared spectroscopy spectra of silk prior to electrospinning (red), post-electrospinning (blue), and after cross-linking (black). (D) Proportion of β-sheet crystallinity in electrospun silk prior to electrospinning, post-electrospinning, and after cross-linking. Mechanical properties of silk, compared with expanded polytetrafluoroethylene (ePTFE) and fresh rat aorta as control scaffolds. (E) Youngs moduli, (F) ultimate tensile strength (UTS), and (G) percentage of elongation. Data are mean ± SEM; n = 9 to 12 (n = 2 for rat aorta). (H) Macroscopic images of electrospun silk graft. Scale bar = 1 mm. (I) Quantification of the maximum pressure before failure. Data are mean ± SEM; n = 6 (n = 3 for rat aorta). (J) Suture pull-out data of silk graft, with rat aorta as a control. Data are mean ± SEM; n = 7 (n = 3 for rat aorta).

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