Figure 1: Cardiovascular Precision Medicine Timeline

2019-06-11T07:07:19Z (GMT) by Alexandra M. Dainis Euan A. Ashley
This timeline highlights key events in the history of precision medicine, such as the introduction of the first precision medicine drugs and the announcement of the Precision Medicine Initiative, as well as specific case studies cited in this review. Notable in this presentation is the explosion of activity in the past 5 years as advances in genome sequencing and genome editing technologies have rapidly increased the speed of basic research and clinical application of precision medicine technologies in cardiovascular medicine. AHA = American Heart Association; CLIA = Clinical Laboratory Improvement Amendments; CML = chronic myelogenous leukemia; FDA = Food and Drug Administration; HCM = hypertrophic cardiomyopathy; iPSCs = induced pluripotent stem cells; LDL-C = low-density lipoprotein cholesterol; LQTS = long QT syndrome.