Figure 9: PP2Ce Expression Impairs Function Recovery Following Ischemia/Reperfusion Injury
AkaikeToru
DuNa
LuGang
MinamisawaSusumu
WangYibin
RuanHongmei
2019
<b>(A)</b> Left ventricle dP/dt max during 15-min global ischemia followed by 60-min reperfusion in isolated hearts from nontransgenic control subjects (control, n = 9) and PP2Ce TG (TG, n = 6) mice. Left ventricle function parameters measured as <b>(B)</b> left ventricular developed pressure (LVDP), <b>(C)</b> systolic pressure increase (dP/dt max), <b>(D)</b> diastolic pressure decrease (dP/dt min), and <b>(E)</b> relaxation time index (Tau) in nontransgenic control subjects (control, n = 9) and PP2Ce TG hearts (n = 6) at basal and 45 min after reperfusion. **p < 0.01 between control and PP2Ce TG groups. #p < 0.05; ##p < 0.01 between corresponding control and PP2Ce TG groups at each time point.